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Therefore, in patients with a low or intermediate pretest chance of PE and age over 50 years, the commonest correction factor is to make use of a cutoff value of age multiplied by 10 in ng/mL. Nonetheless, elevated D-dimer ranges are not specific for venous thrombus because many patients with out deep venous thrombosis (DVT) or PE even have elevated levels (particularly in patients who are hospitalized). Subsequently, additional testing is required when the D-dimer level is elevated or when the pretest chance for PE is high.

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