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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are often characterized by their focus on practical aspects of designing a study which include the recruitment process and consent, adhering and the use of standard equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed various investigators and included participants from various geographical areas. This type of heterogeneity that is crucial for pragmatic trials to be reliable and lessen the chance of bias is also essential. A high degree of heterogeneity, however can result in problems with the design of the trial.

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The aim of pragmatic trials is to replicate real-life scenarios and 프라그마틱 무료슬롯 gain maximum credibility externally. Usually, they are requested by practitioners and policymakers to guide their decisions. They can also be used to determine the cause-effect relationship of an intervention with its outcomes. They should, however, not, be used to replace explanatory studies.

The pragmatism idea is controversial, and 프라그마틱 슬롯 조작 there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which support the physiological hypothesis or clinical hypothesis, as well as pragmatic trials that aid in policy and practice decision-making. They also proposed a framework called PRECIS for pragmatic trials.2 The tool was designed to define the elements of a practical study that includes recruitment, design, implementation of the intervention, and follow-up.

There is a positive trend in the number of pragmatic trials that are published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to remember, however, 프라그마틱 무료체험 슬롯버프 that the majority of studies were conducted in primary-care settings.