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Therefore, researchers speculate that inhibition or harm to the LHb leading to a failure to course of such data could result in random motivation habits. Matsumoto and Hikosaka advised in 2007 that this reward and reward-destructive data within the brain might "be elaborated via the interplay among the many lateral habenula, the basal ganglia, and monoaminergic (dopaminergic and serotonergic) methods" and that the lateral habenula might play a pivotal role in this "integrative function".

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